Obagi Reviews – Acne, Wrinkles, Hyperpigmentation, and More

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Obagi skincare line was developed with the intention to provide cosmetic physicians and medical spas with potent, targeted, and high-quality topical products. Later, Obagi introduced other products to its skincare line that used natural ingredients to allow everybody to use Obagi products.

Today, Obagi treatment system focuses on dealing with skin conditions like wrinkles and fine lines, sun damage, acne, pigmentation, among others. The products comprise the following categories:
  • Acne product line
  • Anti-wrinkle products
  • Skin lighteners
  • Vitamin C Serums
  • Moisturizers and sunblocks
What makes Obagi products stand out from the other brands is its use of high-quality ingredients.
In this article, you will find the best Obagi product for your skin concern, whether it is acne, fine lines and wrinkles, under-eye wrinkles, hyperpigmentation and dark spots, or dry skin.
Acne is a result of a combination of three factors: excess sebum production, P. acnes bacteria, and inflammation. Acne is most common in adolescents and young adults, but can affect people of all ages.
Obagi has developed four products to help people dealing with acne restore natural, clear, and smooth skin.
The products comprise a cleanser, a toner, a lotion, and a moisturizer.
The moisturizer and the lotion contain Benzoyl Peroxide, which is known to effectively kill the acne-causing bacteria, while the toner and the cleanser contain salicylic acid that targets excess oil and helps to clear acne.
Here’s a detailed overview of each of the products:

Obagi Medical CLENZIderm M.D. Daily Care Foaming Cleanser

Obagi Medical CLENZIderm M.D. Daily Care Foaming Cleanser
This light salicylic acid foaming cleanser is perfect for people prone to acne or those with oily skin. The cleanser not only rids of acne but also prevents the skin from further breakouts.
CLENZIderm reaches down into the pores to remove oil, dirt, and other pollutants from the skin, thus unclogging the skin pores and promoting a clearer and healthier complexion. Also, the cleanser’s fortifying pH levels help balance the production of sebum.
The formula also contains menthol, which is great for soothing the skin and reducing skin irritation.
Many users report seeing positive results within the first week.

What We Like

  • Contains 2% salicylic acid
  • Reduces skin breakouts
  • Soothes inflammation
  • Ideal for oily, acne-prone and combination skin
  • No side effects

Obagi CLENZIderm M.D. Pore Therapy

Obagi CLENZIderm M.D. Pore Therapy
This balancing facial toner works very well to unclog pores, clear away dead skin cells, and control excess oil production, preparing your complexion for other blemish-fighting treatments.
It contains glycerin to keep the skin hydrated and prevent dryness, and 2% salicylic acid, which is very effective in clearing the skin from acne.
With regular use, this skin toner will help you achieve a clear, balanced, and smooth complexion.

What We Like

  • Does not dry out the skin
  • Improves your complexion
  • Enhances the results of other acne-prone skin treatments
  • Minimizes pores

Obagi CLENZIderm M.D. Therapeutic Lotion

Obagi CLENZIderm M.D. Therapeutic Lotion
Most people believe that drying out the skin helps reduce acne, on the contrary, hydration is vital to prevent the skin from producing excess sebum, which can often lead to breakouts and clogged pores.
Obagi CLENZIderm M.D. Therapeutic Lotion contains 5% of benzoyl peroxide; it uses a stabilized molecule of benzoyl peroxide that goes directly to the follicles to reach the bacteria that causes acne, thus reducing the potential of benzoyl peroxide to cause irritation.
The formula also contains squalane to provide the skin with moisture and prevent dryness.
Clinical studies have shown that this lotion reduces breakouts in just one week with ongoing positive results through 12 weeks of use.

What We Like

  • Contains benzoyl peroxide to kill bacteria and clear pores
  • Treats breakouts without causing dryness or irritation
  • Rids of breakouts in less than a week
  • Hydrates the skin
  • Lightweight and non-greasy

Obagi CLENZIderm M.D. Therapeutic Moisturizer

Obagi CLENZIderm M.D. Therapeutic Moisturizer
Obagi CLENZIderm M.D. Therapeutic Moisturizer is excellent for people who are experiencing flaking or dryness while using acne treatments. Its high glycerin content keeps your skin hydrated, soft, and comfortable.
It has a gentle, non-comedogenic formula that soothes and protects the skin, while reducing irritation caused by weather elements, makeup, and acne.
This moisturizer is a great product to complement your acne skin care routine for the best results.

What We Like

  • Extremely light
  • Reduces flaking, irritation, tightness, and itching
  • Only need to pump a small amount, and it spreads
  • Non-comedogenic

Best Obagi Products For Fine Lines & Wrinkles

Lines and wrinkles can appear prematurely, especially among people who don’t moisturize their skin, or have not been using sun protection as often as they should have been.
Obagi has a full line of products that address this problem. Your ideal product depends on the severity, skin type, and the area where you have wrinkles.
The products include:

Obagi Medical 360 Retinol 0.5/ Obagi Medical 360 Retinol 1

Obagi Medical 360 Retinol 0.5
Obagi Medical 360 Retinol 1
This product is ideal for minimizing fine lines and wrinkles and is available in two strengths (Retinol 1 and Retinol 0.5). It comes with a unique entrapment technology that dramatically reduces the potential of irritation and rids of wrinkles without causing the skin to flake or develop redness.
Clinical trials reveal that 90% of participants have a firmer skin and less visible fine lines and wrinkles after the third week of use of Obagi 1.0.
Obagi Retinol 0.5 is a great product to introduce retinol in your skincare routine. It contains a lower concentration of 0.5% retinol that gently minimizes the appearance of fine lines and wrinkles.
On the other hand, Obagi’s Retinol 1.0 has a higher concentration of 1% retinol; it fights the signs of aging with minimal skin irritation.
Both formulas also contain jojoba oil and shea butter to hydrate and nourish the skin, as well as vitamins C and E that fight free radicals and provide antioxidant support.

What We Like

  • Eliminate photodamage caused by excessive exposure to the sun
  • Also treat acne and hyperpigmentation
  • Do not irritate the skin

Obagi Medical Professional-C Serum

Obagi Medical Professional-C Serum 10%
Obagi Medical Professional-C Serum 15%
Obagi Medical Professional-C Serum 20% - Best Vitamin C Serums for Oily Skin
Generally, Vitamin C serum is known for its ability to reverse the aging process, even skin tones, and improve the texture of the skin. For Vitamin C serum to deliver these benefits, it has to meet these criteria:
  • Have a PH of 3.5
  • Have a concentration of 10 to 20%
  • Be in ascorbic acid form

Obagi’s Medical Professional-C serum fits these requirements and delivers these benefits perfectly:

  • It reverses the aging process
  • Prevents acne
  • Boosts collagen production
  • Reduces hyperpigmentation
  • Eliminates inflammatory conditions like rosacea
When tested along with other brands like Skinceuticals, Obagi’s Vitamin C showed that it had a superior concentration of 333 ug vs 238 ug. As such, you only need to use a small amount of Obagi’s Medical Professional-C Serum to get lasting results.
The 10% formula is recommended for dry, irritated or sensitive skin, the 15% formula is recommended for most skin types, while the 20% formula is best suited for normal to oily skin.

What We Like

  • Eliminates photodamage
  • Quick absorption and deep penetration into the skin
  • Need to apply a small amount for long-lasting results
  • Also treats hyperpigmentation
  • The blue bottle offers protection against oxidation

Obagi Professional-C Peptide Complex

Obagi Professional-C Peptide Complex
Apart from the Medical Professional-C serum, Obagi has developed another highly effective skincare serum packed with potent ingredients, such as vitamin C, Kinetin and Zeatin, and peptides.
The kinetin and zeatin (plant-sourced ingredients) and vitamin C repair damaged skin, minimize the appearance of skin aging, and revitalize the skin, while the peptides help stimulate collagen production, and dramatically reduce the depth of fine lines and wrinkles.
Other ingredients include Hyaluronic Acid to boost and preserve moisture in the skin, and Aloe Vera and Green Tea to calm skin irritation and fight bacteria.
Obagi’s Professional-C Peptide Complex also contains acetyl octapeptide, clinically known to reduce the depth of wrinkles by 35%.

What We Like

  • Reduces the appearance of wrinkles and fine lines
  • Repairs damaged skin
  • Promotes collagen production
  • Non-Comedogenic
  • Light and nice smell
  • Lightweight

Best Obagi Products For Under-eye Wrinkles

The skin around the eyes is the area where wrinkles are most likely to appear first, as this area has the thinnest and most delicate skin of the human body.
Prolonged sun exposure, genetics, alcohol abuse, poor diet, lack of sleep, as well as environmental factors are all well known to accelerate the development of wrinkles under the eyes.
Obagi has formulated two eye wrinkle products using clinically proven ELASTIderm technology to help support your skin elasticity, and effectively reduce the appearance of under-eye wrinkles.

Obagi Medical ELASTIderm Eye Cream

Obagi Medical ELASTIderm Eye Cream
Obagi’s Medical Elastiderm eye cream is one of the best eye-wrinkle creams in the market, it is clinically proven to significantly reduce the appearance of fine lines and wrinkles around the eyes in as little as two weeks.
The cream helps restore skin elasticity and promote healthy skin appearance by encouraging the production of collagen and elastin, thanks to its bi-mineral complex technology.
The formula also includes Malonic acid that helps stimulate the production of new skin cells, for tighter, healthier, and smoother skin around the eyes, algae extract that works as softener and skin conditioner, and blueberry extract and licorice root that provide antioxidizing properties and remove toxins.
It also contains iron oxide and Mica which provide the skin with brightening benefits.
The cream is designed for:
  • Aging women who want to restore a youthful skin appearance
  • Those who want to restore smooth skin around the eyes
  • People who have crows feet
Be sure to keep the product away from sunlight as direct contact with the sun can de-stabilize the ingredients.

What We Like

  • Strengthens fragile skin
  • Lasts up to three months
  • Eliminates free radical damage
  • Clinically proven to deliver visible results in two weeks
  • Also treats dark circles and puffiness

Best Obagi Products For Hyperpigmentation, Dark Spots, And Melasma

Hyperpigmentation is a result of hormonal changes, genetics, excessive exposure to the sun, and inflammation. The condition manifests in the form of hyperpigmentation, dark spots, or melasma.
To treat the condition, you need to use brightening ingredients that target the spots. One such component is Arbutin, it has been clinically proven to provide brightening benefits.
Vitamin C is another essential ingredient known to provide antioxidizing benefits and preserve the bright, radiant look.
Both obagi’s Clear FX and Blend FX products feature 7% arbutin, antioxidants and lactic acid to brighten and even your skin tone, here’s an overview of both products.

Obagi Nu-Derm Blend Fx

Obagi Nu-Derm Blend Fx
Obagi Nu-Derm Blend Fx is a great gentle and hydroquinone-free cream that targets hyperpigmentation and sun damage; its formula is packed with antioxidants to help smooth and restore skin. It also contains exfoliating ingredients that remove impurities, enhance cell health and restore the radiance of the skin.
Its formula includes 7% arbutin that reduces the appearance of dark spots by inhibiting the production of the enzymes that cause pigmentation, lactic acid that improves cell turnover and brightens the skin, vitamin C that combats free-radical damage and increases skin elasticity, and vitamin E that boosts the skin’s healing.

The effectiveness of this cream is increased when combined with retinol, this cream boosts the reparative process of damaged cells.

To maximize the results, layer Blend Fx with a retinoid or mix them before applying to the face.

What We Like

  • Fast-absorbing
  • Contains 7% arbutin
  • Also improves skin elasticity
  • Hydroquinone-free
  • Gentle

Obagi Nu-Derm Clear Fx

Obagi Nu-Derm Clear Fx
Obagi Nu-Derm Clear Fx is an excellent alternative for people looking for a hydroquinone-free and brightening cream that does not bleach.
It contains the same ingredients as the Obagi Nu-Derm Blend Fx to address hyperpigmentation problems like dark spots, melasma, and the unsightly aftermath of breakouts.
The main difference between the two products is that Clear FX has a larger arbutin molecule, and as a consequence targets pigmentation at the epidermis level, while Blend FX penetrates deeper into the skin with its smaller sized arbutin molecule, and treats the skin at a deeper level, it also prevents melanin formation.
Clear FX can be used morning and night, while Blend FX can be used only at night.

What We Like

  • Lasts up to four months
  • Also improves signs of aging
  • Fast-absorbing
  • Hydroquinone-free
  • Contains 7% arbutin

Best Obagi Products For Dry Skin

Dry skin can be a result of toxins and free radicals, some everyday habits such as the use of aggressive exfoliators, or natural aging. A good moisturizer should help rectify the effects of dry skin. However, many moisturizers in the market hardly provide adequate moisture to the skin.
Obagi moisturizing products contain high-quality moisturizing ingredients like shea butter, Hydromanil, avocado, mango butter, and glycerin to aid in rapid moisturization. Here are the two best Obagi products that will help moisturize your skin:

Obagi Hydrate Facial Moisturizer

Obagi Hydrate Facial Moisturizer
We love Obagi Hydrate Facial Moisturizer; this amazing moisturizer does not only provide intense skin hydration, but also fights fine lines and wrinkles, prevents breakouts and irritation and nourishes the skin.
The product has been formulated using a non-sensitizing, non-irritating, and allergy-tested formula that has been tested clinically to provide deep hydration to the skin; the formula contains hydromanil, shea butter, avocado oil, mango butter and glycerin.
Obagi Hydrate Facial Moisturizer has been designed to retain the natural moisture of the skin while gradually releasing its active ingredients to help you maintain soft and glowing skin.

What We Like

  • Contains shea butter, avocado oil, mango butter, and glycerin
  • Moisturizes the skin for up to eight hours
  • Non-comedogenic

Obagi Hydrate Luxe Moisture-Rich Cream

Obagi Hydrate Luxe Moisture-Rich Cream
Obagi Hydrate Luxe is designed to facilitate the skin’s hydrating functions at night, so that in the morning, your skin looks smoother, more radiant, and plumper.
Continued use also helps eliminate fine lines, improve firmness, skin texture, and overall skin health. Its primary ingredients include:
  • Biomimetic peptides which help firm skin and boost skin defense
  • Avocado, shea butter and mango butter extracts that provide excellent moisturizing benefits to the skin
  • Hydromanil which provides lasting hydration to helps the skin keep moisture

What We Like

  • Improves skin tone
  • Hydrates the skin without feeling heavy
  • Also helps with fine lines and wrinkles
  • Rich formula


Whether you have dry skin, dark spots, acne, hyperpigmentation or other skin condition, you are confident of finding a suitable product on Obagi’s vast skincare line. The beauty of the Obagi treatment system is that each product is formulated using ingredients that can effectively treat the skin condition.
Judy Rose

Hi, it’s Judy!

I’m a passionate skincare specialist and writer. I have more than 7 years of experience as a beauty, fashion, and lifestyle writer and editor, and I’m extremely passionate about what I do.